Periodontal diseases are infections of the gums, which destroy the healthy support of your teeth over time. Dental plaque, a colorless film that forms over your teeth, is the primary culprit of periodontal disease. If it is not thoroughly removed from your teeth by frequent brushing and flossing, over time this plaque erodes the supporting gum tissue and bone that holds the teeth in place. As periodontal disease progresses, it may eventually lead to tooth loss. Unfortunately, even those who brush and flush diligently can develop periodontal disease.